5 Nov 2014 During secondary mechanical hyperalgesia, decreased activity was observed in For example, Simone et al. showed an increase of monkey

Secondary hyperalgesia refers to the sensitization that occurs because of changes in spinal cord processing. For example, through a process of central sensitization, the firing of dorsal horn nociceptors can change dramatically in the setting of injury (produced by either tissue or nerve damage). An example would be when a person has surgery on their elbow, and the pain starts to worsen over time instead of improving. Secondary hyperalgesia This type occurs when the pain seems to spread to Secondary hyperalgesia is due to central neuron sensitization and requires continuous nociceptor input from the zone of primary hyperalgesia for its maintenance.

This chapter hyperalgesia [hi″per-al-je´ze-ah] excessive sensitivity to pain. adj., adj hyperalge´sic. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health Hyperalgesia is a condition of a lowered threshold for pain and an increased response to stimuli that cross that threshold. Primary hyperalgesia occurs in the area of an injury, and secondary PERIPHERAL MECHANISM OF HYPERALGESIA 1.

AU - Larsson, Henrik B W. AU - Dahl, Jørgen Berg. PY - 2015. Y1 - 2015 Secondary hyperalgesia occurs in the areas around the injured site because of nociceptor activation in the central nervous system.

In absence of adequate pain control, the possibility of hyperalgesia, tolerance and progression of obtained within 15-30 minutes of administration of a single tablet, a supplemental (second) 133 micrograms example, falls)

Pharyngitis is associated with hyperalgesia in the pharyngeal tissues, such that merely swallowing induces pain. In inflammatory arthritis, slight movement of the joint leads to pain.

21 May 2018 Opioid-induced hyperalgesia (OIH) is a state of heightened pain become more painful (for example, stroking the skin with a cotton ball Many of the side effects seen with opioids occurs also secondary to opioid rece

Secondary hyperalgesia: It occurs when the pain seems to extend to non-injured tissues or tissues. Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; 'hyper' from Greek ὑπέρ (huper, “over”), '-algesia' from Greek algos, ἄλγος (pain)) is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus. The capsaicin-evoked pain intensity was higher in MCS patients compared with controls (P<0.01, 33 mM). The area of secondary hyperalgesia was larger in both the patient groups compared with controls (P<0.05) at both capsaicin concentrations. Temporal summation was increased in MCS patients compared with controls(P<0.01). Because secondary hyperalgesia pain thresholds were not matched across participants, the pin-prick stimulation used to evoke secondary hyperalgesic pain is not as likely to engage the brain network supporting secondary hyperalgesia in individuals with high secondary hyperalgesic pain thresholds relative to individuals with low thresholds.

In inflammatory arthritis, slight movement of the joint leads to pain. Micturition in the presence of a urinary tract infection is painful, again reflecting the presence of hyperalgesia.
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Secondary hyperalgesia is characterized by a leftward shift of the stimulus-response function for noxious mechanical stimuli. In order to define the afferent pathways involved in inducing central Hyperalgesia is defined as "An increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves".

For example, through a process of central 21 May 2018 Opioid-induced hyperalgesia (OIH) is a state of heightened pain become more painful (for example, stroking the skin with a cotton ball Many of the side effects seen with opioids occurs also secondary to opioid rece Reduction in secondary hyperalgesia was associated with reduced pain catastrophizing example, expectation of hyperalgesia can block analgesic effects.
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Tex efter brännskada = hyperalgesia (from av sensitization) --> stimuli känns som mkt mer pga redan skadad Image: Primary vs secondary hyperalgesia?

Se hela listan på findatopdoc.com A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol. Madden VJ, Bedwell GJ, Chikezie PC, Rice ASC, Kamerman PR Syst Rev 2019 Aug 19;8(1):208. doi: 10.1186/s13643-019-1120-7.